一项研究发现,妊娠和母乳喂养可能会通过增加长效免疫细胞来降低乳腺癌的风险。
Pregnancy and breastfeeding may lower breast cancer risk by boosting long-lasting immune cells, a study finds.
在《自然》出版的一份新研究报告显示,妊娠和哺乳可引发长期免疫反应,从而降低乳腺癌的风险。 澳大利亚科学家主导的研究发现,这些经验促进了乳房组织中保护性的CD8+T细胞。
A new study published in Nature reveals that pregnancy and breastfeeding may reduce breast cancer risk by triggering a long-lasting immune response, with research led by Australian scientists finding that these experiences boost protective CD8+ T-cells in breast tissue.
这些免疫细胞可能已经演变为防治乳腺炎等感染,可以持续数十年,并且与小鼠和人类体内具有侵略性的三胞胎阴性乳腺癌增长缓慢有关。
These immune cells, which may have evolved to fight infections like mastitis, can persist for decades and are linked to slower growth of aggressive triple-negative breast cancer in both mice and humans.
哺乳妇女患肿瘤的T细胞密度较高,存活率较好。
Women who breastfed showed higher T-cell density in tumors and better survival rates.
根据对260多名妇女和鼠标模型的分析,研究结果可能导致新的预防疗法,尽管研究人员强调母乳喂养是一种个人选择,而不是一种有保障的癌症预防方法。
The findings, based on analysis of over 260 women and mouse models, could lead to new preventive therapies, though researchers stress breastfeeding is a personal choice and not a guaranteed cancer prevention method.