在研究中,自然植物化合物加速了糖尿病脚溃疡的愈合,为预防截肢提供了潜在的低成本治疗方法。
A natural plant compound sped healing of diabetic foot ulcers in studies, offering a potential low-cost treatment to prevent amputations.
纳加兰大学的研究人员发现,食用植物的一种天然化合物,即西纳西酸,通过激活SIRT1途径,在临床前期研究中加快糖尿病脚溃疡的愈合速度,剂量较低(20毫克/千克),其效果大于较高剂量。
Researchers at Nagaland University found that sinapic acid, a natural compound in edible plants, speeds healing of diabetic foot ulcers in preclinical studies by activating the SIRT1 pathway, with a lower dose (20 mg/kg) showing greater effectiveness than a higher dose.
化合物改善了组织修补,减少了炎症和氧化性压力,并增强了代谢健康。
The compound improved tissue repair, reduced inflammation and oxidative stress, and enhanced metabolic health.
在《自然科学报告》中公布的调查结果表明,可以提供安全、负担得起的口服治疗,减少截肢,特别是在服务不足的地区。
Published in Nature Scientific Reports, the findings suggest a safe, affordable oral treatment that could reduce amputations, especially in underserved areas.
该小组计划试点人类试验,以评估其现实世界的潜力。
The team plans pilot human trials to assess its real-world potential.