根据最新研究, 局部类固醇可以通过阻断Garp来治疗黑色素瘤, Topical steroids may treat melanoma by blocking Garp, helping the immune system fight cancer, new research shows.

根据英国曼彻斯特癌症研究所的研究，外用类固醇乳膏可能通过阻断 Garp 蛋白来帮助对抗黑色素瘤，Garp 蛋白有助于癌症逃避免疫系统。 Topical steroid creams may help combat melanoma by blocking the Garp protein, which helps cancer evade the immune system, according to research from the Cancer Research UK Manchester Institute. 虽然类固醇通常抑制豁免,但研究发现,在加普受抑制时,它们可引发抗癌免疫反应。 Though steroids typically suppress immunity, the study found they can trigger an anti-cancer immune response when Garp is inhibited. 对2 000多名病人和40个肿瘤样本的分析表明,与存活时间较长有关的卡普水平较低。 Analysis of over 2,000 patients and 40 tumor samples showed lower Garp levels linked to longer survival. 研究人员认为,将Garp作为目标可能导致对黑瘤和可能其他癌症的新治疗,药物研制和临床试验正在进行。 Researchers believe targeting Garp could lead to new treatments for melanoma and possibly other cancers, with drug development and clinical trials underway. 这些研究结果发表在《癌症发现》上，挑战了关于类固醇和免疫力的传统观点。 The findings, published in Cancer Discovery, challenge conventional views on steroids and immunity.