早期更年期与更高的痴呆风险相关; 荷尔蒙疗法可能有帮助, 但需要更多的研究. Early menopause linked to higher dementia risk; HRT may help, but more research is needed.

将早期更年期与高痴呆风险和荷尔蒙替代疗法(HRT)与潜在保护联系起来的新研究已在《阿尔茨海默氏病期刊》上公布。 A new study linking early menopause to higher dementia risk and hormone replacement therapy (HRT) to potential protection has been published in the Journal of Alzheimer’s Disease. 研究人员分析了Framingham心脏研究中1 329名妇女的数据,发现长期接触雌激素 -- -- 通过更年期、更高的雌激素水平或更多的子女 -- -- 与更好的认知功能和更大的大脑体积有关。 Analyzing data from 1,329 women in the Framingham Heart Study, researchers found that longer lifetime exposure to estrogen—through later menopause, higher estrogen levels, or more children—was associated with better cognitive function and larger brain volumes. 虽然HRT可能降低痴呆风险,但研究人员强调需要进一步研究,并谨慎不做出最终结论. While HRT may lower dementia risk, researchers stress the need for further study and caution against drawing definitive conclusions. 调查结果突出说明了痴呆症中与性别有关的差别,因为妇女占老年痴呆症病例的近三分之二。 The findings highlight sex-related differences in dementia, as women make up nearly two-thirds of Alzheimer’s cases.