科学家从模仿胚胎早期发育的人类干细胞中创建了实验室培育的血液结构。
Scientists created lab-grown blood-producing structures from human stem cells that mimic early embryonic development.
科学家从人类干细胞中创造出实验室生长出来的类似胚胎的结构,称为血型,在两周内产生血细胞,模仿人类早期发展。
Scientists have created lab-grown embryo-like structures called hematoids from human stem cells that produce blood cells within two weeks, mimicking early human development.
这些结构在第2天形成3个基本组织层,在第13天显示可见的红色血细胞组,复制阶段相当于胚胎发育的4至5周——通常无法进行研究。
These structures form the three primary tissue layers by day two and show visible red blood cell clusters by day 13, replicating stages equivalent to weeks four to five of embryonic development—typically inaccessible for study.
与真正的胚胎不同,血型缺乏蛋白沙囊和胎盘,从而阻止了进一步生长。
Unlike real embryos, hematoids lack a yolk sac and placenta, preventing further growth.
该模型有助于对血液和免疫系统形成、疾病建模、药物测试和再生医学进行研究,包括利用病人自己的细胞进行可能的治疗。
The model enables research into blood and immune system formation, disease modeling, drug testing, and regenerative medicine, including potential therapies using a patient’s own cells.
这些调查结果发表在小组报告中,由剑桥大学Gurdon研究所牵头,在Wellcome的支持下,通过剑桥企业公司获得专利。
The findings, published in Cell Reports and led by the University of Cambridge’s Gurdon Institute with support from Wellcome, are patented through Cambridge Enterprise.