Dexamethasone通过增强免疫细胞功能和减少炎症,促进结核病治疗,但专家敦促对副作用采取谨慎态度。
Dexamethasone boosts TB treatment by enhancing immune cell function and reducing inflammation, but experts urge caution due to side effects.
根据"科学报告"杂志的一项新研究, 类固醇德克萨米他可以通过提高巨细胞杀死结核菌的能力, 提高细胞存活率, 通过改善自和体酸性, 减少细菌负载, 提高结核病治疗效果.
A new study in Scientific Reports finds that dexamethasone, a steroid, can enhance tuberculosis treatment by boosting macrophages' ability to kill Mycobacterium tuberculosis, improve cell survival, and reduce bacterial load through improved autophagy and phagosomal acidification.
它还通过降低亲食性和抗炎性细胞外皮和减少液解作用来平衡免疫反应,同时限制有害的炎症,同时又不削弱防御能力。
It also balances immune response by lowering both pro- and anti-inflammatory cytokines and reducing glycolysis, limiting harmful inflammation without weakening defense.
研究结果支持重新考虑在抗生素的同时使用类固醇的目标,特别是在发炎性肺结核病例中,尽管专家们告诫不要因副作用而过度使用,并强调需要仔细制定规程和进一步研究。
The findings support reconsidering targeted steroid use alongside antibiotics, especially in inflammatory TB cases, though experts caution against overuse due to side effects and stress the need for careful protocols and further research.