意大利研究人员开发了一种鼻鼻喷剂,配有锂装金纳米粒子,向大脑提供药物,扭转小鼠的记忆丧失,其副作用较小。
Italian researchers developed a nasal spray with lithium-loaded gold nanoparticles that delivers medication to the brain, reversing memory loss in mice with fewer side effects.
使用锂装金纳米粒的鼻涕喷雾在治疗阿尔茨海默氏病和双极紊乱等脑疾病方面显示出希望,直接向大脑提供药物,绕过血脑屏障。
A nasal spray using lithium-loaded gold nanoparticles is showing promise in treating brain disorders like Alzheimer’s and bipolar disorder by delivering medication directly to the brain, bypassing the blood-brain barrier.
由意大利研究人员开发的非侵入方法针对河马坎普斯,抑制了与记忆丧失和疾病发展有关的GSK-3-β酶。
Developed by Italian researchers, the non-invasive method targets the hippocampus and inhibits the GSK-3β enzyme linked to memory loss and disease progression.
在老鼠研究中,它以较低的锂剂量和比口服较少的副作用,扭转了记忆缺陷。
In mouse studies, it reversed memory deficits with lower lithium doses and fewer side effects than oral administration.
该技术在国际上获得专利,目前正在进一步研究,以保障安全和更广泛地使用,并有可能在今后进行人类试验。
The technology, patented internationally, is being studied further for safety and broader use, with potential for human trials in the future.