一项研究发现 子宫脂肪的代谢活动 不仅仅是数量 与激进的子宫内癌有联系 Visceral fat's metabolic activity, not just amount, links to aggressive endometrial cancer, a study finds.

在EANM'25提出的一项新的研究中,将代谢性活性内脏脂肪与内脏器官周围的代谢性内脏脂肪——与更激进的内脏癌症联系起来,而不考虑脂肪的体积。 A new study presented at EANM'25 links metabolically active visceral fat—fat around internal organs—to more aggressive endometrial cancer, independent of fat volume. 研究人员分析了274名妇女的PET/CT扫描结果,发现内脏脂肪中较高的葡萄糖摄入量与晚期癌症阶段和淋巴结扩散相关。 Analyzing PET/CT scans of 274 women, researchers found higher glucose uptake in visceral fat correlated with advanced cancer stages and lymph node spread. 调查结果显示,脂肪的生物活动受炎症、胰岛素抗药性和信号分子的驱动,可能会刺激肿瘤的生长。 The findings suggest that the fat’s biological activity, driven by inflammation, insulin resistance, and signaling molecules, may fuel tumor growth. 虽然目前的成像尚不可靠供临床使用,但今后在定量成像和AI方面的进步可能会改善风险评估和治疗。 While current imaging isn’t yet reliable for clinical use, future advances in quantitative imaging and AI may improve risk assessment and treatment.