施特拉林的英国病人被警告要避免葡萄汁、酒精和某些补充剂, UK patients on sertraline warned to avoid grapefruit juice, alcohol, and certain supplements due to dangerous interactions.

英国人食用普通抗抑郁药Sertraline, 受到国民健康服务署的警告, 避免葡萄汁、酒精及某些补充剂, People in the UK taking sertraline, a common antidepressant, have been warned by the NHS to avoid grapefruit juice, alcohol, and certain supplements due to potential dangerous interactions. 葡萄果汁可以阻塞CYP3A4酶,增加副作用的风险,从而增加血液中的血浆浓度水平。 Grapefruit juice can increase sertraline levels in the blood by blocking the CYP3A4 enzyme, raising the risk of side effects. Seville橙子和Tangelos也可能产生类似影响。 Similar effects may occur with Seville oranges and tangelos. 酒精可能会降低药效, 并加剧副作用。 Alcohol may reduce the drug’s effectiveness and worsen side effects. 塞特拉林也可能与血液稀释剂,NSAIDs,MAOI抗抑郁药,圣约翰草和其他补充剂产生不良相互作用. Sertraline can also interact poorly with blood thinners, NSAIDs, MAOI antidepressants, St John’s wort, and other supplements. 敦促患者向医生通报他们使用的所有药物和补充剂。 Patients are urged to inform their doctor about all medications and supplements they are using.