一项新的血液测试预测严重的肝脏疾病提前10年达到88%的准确度。 A new blood test predicts severe liver disease up to 10 years early with 88% accuracy.

由Karolinska Institut开发并在2025年9月29日发表在《BMJ》上的新血液测试模型“CORE”,通过年龄、性别和三个肝酶(AST、ALT、GGT)的常规血液测试,可以提前10年预测严重的肝病——如肝硬化或肝癌。 A new blood test model called CORE, developed by Karolinska Institutet and published in The BMJ on September 29, 2025, can predict severe liver disease—such as cirrhosis or liver cancer—up to 10 years in advance using routine blood tests for age, sex, and three liver enzymes (AST, ALT, GGT). 对480,000多名斯德哥尔摩居民进行了测试,并进行了长达30年的后续跟踪,它正确地查明了今后88%的病例,超过了FIB-4方法。 Tested on over 480,000 Stockholm residents with up to 30 years of follow-up, it correctly identified 88% of future cases, outperforming the FIB-4 method. 该工具作为网上计算器,显示了初级保健使用的前景,已在芬兰和联合王国得到验证,但还需要对糖尿病或肥胖症等高风险群体进行进一步研究。 The tool, available as a web-based calculator, shows promise for use in primary care and has been validated in Finland and the UK, though further study is needed in high-risk groups like those with diabetes or obesity.