在过时的治疗准则和对一线药物的抗药性推动下,东南亚新生儿抗生素性感染正在上升。 Antibiotic-resistant infections in Southeast Asian newborns are rising, driven by outdated treatment guidelines and resistance to first-line drugs.

一项新的研究发现,东南亚各地新生儿抗生素感染呈上升趋势,大多数细菌感染都发生在耐世卫组织建议的第一线治疗的婴儿身上。 A new study finds antibiotic-resistant infections in newborns are rising across Southeast Asia, with most bacterial infections in infants resistant to WHO-recommended first-line treatments. 研究人员对来自五个国家的近15 000个血液样本进行了分析。 研究人员说,基于高收入国家的过时准则未能反映当地的抗药性模式,特别是E. Coli 和 Klebsiella 等Gram阴性细菌的抗药性模式。 Analyzing nearly 15,000 blood samples from five countries, researchers say outdated guidelines based on high-income nations fail to reflect local resistance patterns, especially for Gram-negative bacteria like E. coli and Klebsiella. 专家警告说,如果不更新区域治疗规程,婴儿死亡率就会上升,并呼吁对儿科抗生素和诊断进行紧急投资,因为真菌感染也大大助长严重病例。 Experts warn of rising infant mortality without updated regional treatment protocols and call for urgent investment in pediatric antibiotics and diagnostics, as fungal infections also contribute significantly to severe cases.