根据2025年的一项研究,更年期改变女性的MS发作和进步,影响症状、并发症和死亡率。 Menopause alters MS onset and progression in women, affecting symptoms, comorbidities, and mortality, per a 2025 study.

ECTRIMS 2025年提交的一项新研究分析了864 MS病人发现更年期严重影响了MS的开始和妇女的进展。 A new study presented at ECTRIMS 2025 analyzing 864 MS patients found menopause significantly affects how MS begins and progresses in women. 绝经前妇女更经常出现先天性神经症状,精神病发病率更高,而绝经后妇女和男子更有可能出现脊髓炎以及心血管疾病和新陈代谢紊乱等更频繁的并发症。 Premenopausal women more often had optic nerve symptoms at onset and higher rates of psychiatric conditions, while postmenopausal women and men were more likely to have spinal cord onset and greater comorbidities like cardiovascular disease and metabolic disorders. 更年期后妇女和男子的死亡率也较高,这表明荷尔蒙变化可能影响免疫反应和神经退化。 Postmenopausal women and men also had higher mortality rates, suggesting hormonal changes may influence immune responses and neurodegeneration. 调查结果突出表明,需要基于生命阶段的个性化MS护理,对绝经前妇女进行复发监测,对绝经后妇女和男子进行残疾和神经退化预防。 The findings highlight the need for personalized MS care based on life stage, with premenopausal women monitored for relapses and postmenopausal women and men targeted for disability and neurodegeneration prevention.