María Branyas Morera是全世界最年长的人, 直到她2024年去世,
María Branyas Morera, the world’s oldest person until her 2024 death, had a youthful biological profile linked to genetics, diet, and lifestyle, according to a study.
一位117岁的妇女玛利亚·布兰亚斯·莫雷拉(María Branyas Morera)是世界上最年长的人,直到她2024年去世为止,她为人类的极端长寿提供了难得的真知灼见。
A 117-year-old woman, María Branyas Morera, the world’s oldest person until her 2024 death, provided rare insights into extreme human longevity.
西班牙研究人员研究她的遗传学、微生物和生活方式,发现尽管年纪已高,但仍有年轻生物特征,包括低发炎、高效新陈代谢、强健的免疫系统以及富含有益细菌的肠胃微生物。
Spanish researchers studied her genetics, microbiome, and lifestyle, finding a youthful biological profile despite advanced age, including low inflammation, efficient metabolism, a robust immune system, and a gut microbiome rich in beneficial bacteria.
她的遗传变异与心脏和大脑健康、低胆固醇和降低疾病风险有关,还有10至23岁的遗传年龄比其时龄小10至23岁。
She had genetic variants linked to heart and brain health, low cholesterol, and reduced disease risk, along with an epigenetic age 10 to 23 years younger than her chronological age.
虽然她的端粒很短, 但整体生物学表明她有弹性.
While her telomeres were short, her overall biology suggested resilience.
地中海饮食、积极生活方式和强大的社会联系可能有所贡献,但科学家们强调,遗传学、生活方式和机会都发挥了作用。
A Mediterranean diet, active lifestyle, and strong social ties likely contributed, but scientists stress that genetics, lifestyle, and chance all played roles.
研究结果发表在《细胞报告医学》中,突出了更健康老龄化的潜在途径,尽管需要进行更大的研究,以确认更广泛的模式。
The findings, published in Cell Reports Medicine, highlight potential pathways for healthier aging, though larger studies are needed to confirm broader patterns.