杜克研究发现,在压力下, 胰腺甲型细胞会刺激GLP-1, 为2型糖尿病提供天然血液糖控制。 Duke study finds pancreatic alpha cells boost GLP-1 during stress, offering natural blood sugar control for type 2 diabetes.

杜克大学的一项研究发现,胰腺α细胞自然会产生比以前想象的更具生物活性GLP-1的GLP-1,尤其是在代谢压力下,这为改进2型糖尿病血糖控制提供了一种潜在的内部机制。 A Duke University study finds that pancreatic alpha cells may naturally produce more bioactive GLP-1 than previously believed, especially during metabolic stress, offering a potential internal mechanism to improve blood sugar control in type 2 diabetes. 与先前的假设不同的是,这些细胞似乎从Glucagon生产转向GLP-1生产,GLP-1证明对胰岛素释放的刺激力更强。 Unlike earlier assumptions, these cells appear to switch from glucagon to GLP-1 production, with GLP-1 proving a stronger stimulator of insulin release. 研究人员利用先进的探测方法,确认了活跃的GLP-1级GLP-1,建议阿尔法细胞发挥内置后备系统的作用。 Using advanced detection methods, researchers confirmed active GLP-1 levels, suggesting alpha cells act as a built-in backup system. 这种发现可能导致新的疗法,加强人体自身的GLP-1生产,减少对外部药物的依赖。 This discovery could lead to new therapies that enhance the body’s own GLP-1 production, reducing reliance on external drugs.