硝基苯(强力合成类阿片)比芬太尼强20x,正在导致美国超剂量、逃避检测和Narcan的致命剧增。
Nitazenes, potent synthetic opioids 20x stronger than fentanyl, are driving a deadly surge in U.S. overdoses, evading detection and Narcan.
据医学专家和缉毒署称,Nitazenes-能动合成类阿片死灰复燃,比芬太尼强20倍,给美国公众健康带来越来越大的威胁。
A resurgence of Nitazenes—potent synthetic opioids 20 times stronger than fentanyl—poses a growing public health threat in the U.S., according to medical experts and the DEA.
这些药物最初是1950年代开发的,但从未获准用于医疗用途,现在这些药物正在中国制造,并掺入其他非法药物,导致吸毒过量增加。
Originally developed in the 1950s but never approved for medical use, these drugs are now being manufactured in China and mixed into other illicit drugs, leading to a rise in overdoses.
与芬太尼不同,Nitazenes对Narcan有抗药性,需要多剂量才能逆转,标准的药物测试往往无法检测,使治疗和诊断复杂化。
Unlike fentanyl, Nitazenes are resistant to Narcan, requiring multiple doses for reversal, and standard drug tests often fail to detect them, complicating treatment and diagnosis.
2019年至2023年期间,田纳西州报告了90多起与Nitazenes有关的致命过量。
Over 90 fatal overdoses linked to Nitazenes were reported in Tennessee between 2019 and 2023.
专家们敦促扩大使用纳洛酮和药物检测带的机会,同时呼吁对长期影响和治疗对策进行更多的研究。
Experts urge expanded access to naloxone and drug testing strips, while calling for more research on long-term effects and treatment responses.