研究人员发现,在胰岛素生产细胞中提振硅酸可以预防1型糖尿病。
Researchers find that boosting sialic acid in insulin-producing cells may prevent type 1 diabetes.
Mayo诊所研究人员发现,糖分子 -- -- 硅酸 -- -- 有助于癌症细胞摆脱免疫系统,也可以保护产生1型糖尿病的胰岛素乙型细胞。
Mayo Clinic researchers have discovered that a sugar molecule, sialic acid, which helps cancer cells evade the immune system, can also protect insulin-producing beta cells in type 1 diabetes.
通过对这些细胞进行工程设计,以生产更多的西亚酸,这些细胞在临床前模型中有效预防糖尿病的90%。
By engineering these cells to produce more sialic acid, they were 90% effective in preventing diabetes in preclinical models.
这种方法可能导致出现新的治疗方法,保护乙型细胞,而没有广泛的免疫抑制。
This method could lead to new treatments that protect beta cells without broad immune suppression.