加州大学洛杉矶分校研究人员发现,JAK抑制剂可能防止和扭转癌症免疫疗法引起的糖尿病。 UCLA researchers find JAK inhibitors may prevent and reverse diabetes caused by cancer immunotherapy.

加州大学洛杉矶分校的研究人员确定了使用JAK抑制剂(一种自发免疫药物)的潜在战略,以防止和扭转癌症免疫疗法引起的1型糖尿病。 Researchers at UCLA identified a potential strategy using JAK inhibitors, a class of autoimmune drugs, to prevent and reverse type 1 diabetes caused by cancer immunotherapy. 这一突破涉及将特定免疫细胞作为目标,同时不降低癌症治疗的有效性。 This breakthrough involves targeting specific immune cells without reducing the effectiveness of cancer treatment. 目前正在计划进行人类第一次临床试验,对在免疫治疗后患糖尿病的癌症患者进行这一方法的测试。 A first-in-human clinical trial is being planned to test this approach in patients with cancer who develop diabetes after immunotherapy.