研究表明肠道和口腔的细菌变化 可能预示帕金森病人的认知下降 Study suggests bacteria changes in gut and mouth may predict cognitive decline in Parkinson's patients.

King's College London最近的研究表明,帕金森病人的肠道和口腔细菌的变化可能是症状恶化(包括认知下降)的预警信号。 Recent research from King's College London indicates that changes in gut and mouth bacteria in Parkinson's disease patients could be an early warning sign of worsening symptoms, including cognitive decline. 研究人员通过使用人工智能分析有轻度认知障碍、痴呆症和健康个人患者的样本,发现可能源自口腔的有害细菌释放出毒素,可能会损害肠组织并可能影响大脑。 By using AI to analyze samples from patients with mild cognitive impairment, dementia, and healthy individuals, researchers found that harmful bacteria, likely originating from the mouth, release toxins that can damage gut tissue and potentially affect the brain. 这表明,保持口腔和直肠健康可以支持改善帕金森氏病的疾病管理,毒素可以用作标记,用以识别患痴呆症风险较高的患者。 This suggests that maintaining oral and gut health could support better disease management in Parkinson's, and the toxins could be used as markers to identify patients at higher risk of dementia.