研究将E.大肠杆菌的毒素共性与年轻成人早期直肠癌的增加联系起来。 Study links toxin colibactin from E. coli to increased early-onset colorectal cancer in young adults.

加利福尼亚圣迭戈大学最近的研究表明,由某些E.大肠杆菌菌株生产的称为同性活性毒素可能与早期直肠癌发病率上升有关。 Recent research from the University of California San Diego suggests that a toxin called colibactin, produced by certain E. coli strains, may be linked to the rising rates of early-onset colorectal cancer. 研究发现,与 colibactin 相关的 DNA 突变在 40 岁以下的患者中比 70 岁以上的患者更为常见,这表明可能在生命早期暴露于该毒素. The study found that DNA mutations associated with colibactin were 3.3 times more common in patients under 40 than those over 70, indicating potential early-life exposure to the toxin. 研究人员正在研究通过便样本检测胆肠杆菌素暴露的非侵入性测试. Researchers are now working on noninvasive tests to detect colibactin exposure through stool samples.