心脏病发作严重性随时间而变化 与身体的节奏有关 研究发现 Heart attack severity varies by time of day, linked to body's circadian rhythm, study finds.

研究人员发现心脏病发作的严重性 和身体的心律有联系 Researchers have found a link between heart attack severity and the body's circadian rhythm. 蛋白质BMAL1和HIF2A控制心脏对低氧水平的反应,其目标为AREG基因,影响心脏损伤的程度。 Proteins BMAL1 and HIF2A, which regulate the heart's response to low oxygen levels, target a gene called AREG, affecting the extent of heart damage. 与下午3时相比,大约凌晨3点左右的心脏病发作造成的伤害更大。 研究人员认为,通过时间利用身体内部钟进行药物治疗,可以向心脏提供重要的保护,为治疗开辟新的途径。 Heart attacks around 3 a.m. cause more damage compared to those at 3 p.m. By timing drug treatments with the body's internal clock, researchers suggest significant protection could be provided to the heart, opening new avenues for treatment.