研究表明,对70岁以上长期使用激素替代疗法的妇女而言,这种疗法可能会增加阿尔茨海默氏病的风险。 Hormone replacement therapy may increase Alzheimer's risk in women over 70 who used it long-term, study suggests.

更年期的荷尔蒙替代疗法(HRT)可能会加速Tau的积累,Tau是一种与阿尔茨海默氏病相关的蛋白质,特别是10多年前使用高血压疗法的70岁以上妇女。 Hormone replacement therapy (HRT) for menopause may accelerate the buildup of tau, a protein linked to Alzheimer's disease, especially in women over 70 who used HRT more than a decade ago. 年幼妇女没有表现出更多的Tau累积,这表明在更年期早期使用HRT会更安全。 Younger women did not show increased tau accumulation, suggesting HRT could be safer when used earlier in menopause. 研究人员建议与医生讨论HRT的风险和好处, 尤其是对年长的女性. Researchers advise discussing the risks and benefits of HRT with doctors, particularly for older women.