科学家确定高癌症致脂肪损失的蛋白质关键因素,提出新的治疗方法。 Scientists identify protein key to fat loss in advanced cancer, suggesting new treatments.

中国科学家发现,一种叫作大型迁徙抑制因子(MIF)的蛋白质是患有缓冲症的先进癌症患者不可逆转地丧失脂肪的关键。 Chinese scientists have found that a protein called macrophage migration inhibitory factor (MIF) is key to irreversible fat loss in advanced cancer patients with cachexia. 这种导致显著体重减轻和肌肉衰竭的病情,占癌症死亡的20%,而MIF引发脂肪组织的慢性炎症,使这种病情恶化. This condition, which causes significant weight loss and muscle wasting and accounts for 20% of cancer deaths, is exacerbated by MIF triggering chronic inflammation in fat tissue. 研究人员发现,阻断MIF可以缓解小鼠的这些症状,从而有可能带来新的治疗方法,以改善癌症患者的生活质量和生存率. The researchers discovered that blocking MIF could alleviate these symptoms in mice, potentially leading to new treatments to improve quality of life and survival for cancer patients.