研究人员确定了一种可导致新的阿尔茨海默氏病治疗的Tau蛋白质变异物。 Researchers identify a tau protein variant that could lead to new Alzheimer's treatments.

科隆大学的研究人员已经确定了一种称为1N4R的托伊蛋白蛋白的具体变体,该蛋白在阿尔茨海默氏病中起着关键作用。 Researchers at the University of Cologne have identified a specific variant of the tau protein, called 1N4R, which plays a crucial role in Alzheimer's disease. 他们利用人类干细胞,发现这种变异介介介出脑细胞中蛋白凝聚物的毒性效应。 Using human stem cells, they found that this variant mediates the toxic effects of protein clumps in brain cells. 这一发现可能导致针对1N4R Tau蛋白质的新治疗,尽管还需要进一步研究以发展临床应用。 This discovery could lead to new treatments targeting the 1N4R tau protein, though further research is needed to develop clinical applications.