研究发现,细胞虫甲状腺病毒通过增加炎症,使早期婴儿的严重肠道疾病NEC恶化。
Study finds cytomegalovirus worsens NEC, a severe intestinal condition in premature babies, by increasing inflammation.
一项新的研究显示,一种常见的病毒,即细胞球菌病毒(CMV),可能加剧肠结肠炎(NEC)的坏死,这是早产婴儿的一种严重的肠道疾病。
A new study shows that cytomegalovirus (CMV), a common virus, can worsen necrotizing enterocolitis (NEC), a severe intestinal condition in premature babies.
研究人员发现,与没有这种病毒的老鼠相比,患有CMV的老鼠的组织损伤和死亡率较高。
Researchers found that mice with CMV had higher rates of tissue damage and death compared to those without the virus.
CMV感染触发了增加炎症和中断新陈代谢的路径,提高了免疫蛋白TLR4的浓度。
CMV infection triggered pathways that increased inflammation and disrupted metabolism, boosting levels of the immune protein TLR4.
这可能为NEC治疗带来新的药物目标。
This could lead to new drug targets for NEC treatment.