研究人员在神经元中发现有毒蛋白质凝聚物,不是寡头催化细胞,而是驱动多种系统萎缩。
Researchers find toxic protein clumps in neurons, not oligodendrocytes, drive Multiple System Atrophy.
来自新西兰和澳大利亚的研究人员发现,多系统萎缩是一种严重的神经退化性疾病,主要是由神经元中的有毒蛋白囊驱动的,而不是如先前设想的那样由寡头催化细胞驱动的。
Researchers from New Zealand and Australia have found that Multiple System Atrophy (MSA), a severe neurodegenerative disease, is primarily driven by toxic protein clumps in neurons, not oligodendrocytes as previously thought.
这些碎屑扰乱了神经元的核心 导致神经元的毁灭
These clumps disrupt the neuron's nucleus, leading to its destruction.
这种发现可能导致针对这些综合体的新治疗,并有可能阻止疾病的蔓延。
This discovery could lead to new treatments targeting these aggregates and potentially halt the disease's progression.