研究人员发现乙型肝炎的潜在新治疗途径,针对的是关键的病毒基因。
Researchers find potential new treatment path for hepatitis B, targeting a key viral gene.
纪念斯隆凯特林癌症中心,威尔康奈尔医学院和洛克菲勒大学的研究人员发现了B型肝炎病毒 (HBV) 感染的潜在脆弱性,这可能导致新的治疗方法.
Researchers from Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, and The Rockefeller University have identified a potential vulnerability in hepatitis B virus (HBV) infection, which could lead to new treatments.
该研究显示,使用已在癌症试验中的化合物,可以破坏HBV在宿主细胞中感染的关键病毒基因.
The study revealed that a key viral gene essential for HBV to establish infection in host cells can be disrupted using a compound already in cancer trials.
目前的治疗可以阻止病毒的复制,但不能从细胞中完全清除病毒。
Current treatments can stop virus replication but do not fully clear it from cells.
这一发现可以为开发新药物以防治慢性乙肝感染铺平道路,这种感染影响到世界人口的近5%,并导致肝癌。
This discovery could pave the way for developing new drugs to combat chronic HBV infection, affecting nearly 5% of the world's population and causing liver cancer.