研究人员开发新的PET成像探测器,以探测炎症,旨在进行人类试验。 Researchers develop new PET imaging probe to detect inflammation, aiming for human trials.

Dana-Farber癌症研究所的研究人员开发了一个新的PET成像探测器CD45-PET,以以免疫细胞上的标记CD45为目标,检测发炎。 Researchers at Dana-Farber Cancer Institute have developed a new PET imaging probe, CD45-PET, to detect inflammation by targeting CD45, a marker on immune cells. 该探测器显示动物模型具有潜力,与临床症状和组织分析密切相关。 The probe has shown potential in animal models, correlating well with clinical symptoms and tissue analysis. 此外,还开发了人类版的探测器,并在人性化的鼠标模型中成功地进行了测试。 A human version of the probe has also been developed and tested successfully in humanized mouse models. 该小组现在的目标是临床试验,目标是利用CD45-PET指导抗炎治疗和诊断炎症。 The team is now aiming for clinical trials, with the goal of using CD45-PET to guide anti-inflammatory treatments and diagnose inflammatory conditions.