Penn研究者发现,饮食诱导会提高CAR T细胞癌治疗的效果;试验还在进行中。 Penn researchers find ketogenic diet may boost CAR T cell cancer therapy effectiveness; trial ongoing.

宾夕法尼亚大学的研究人员发现,通过增加乙型氢氧丁酸(BHB)可提高CAR T细胞治疗的效果,从而增强CAR T细胞防治癌症的能力。 Researchers at the University of Pennsylvania found that a ketogenic diet could enhance CAR T cell therapy effectiveness by increasing beta-hydroxybutyrate (BHB), which boosts CAR T cells' ability to fight cancer. 目前正在进行第一阶段临床试验,以评估将BHB补充剂与CAR T细胞疗法相结合的安全性和有效性。 A Phase I clinical trial is underway to assess the safety and efficacy of combining BHB supplementation with CAR T cell therapy. 这可以为改进癌症治疗结果提供一种具有成本效益和低毒性的办法。 This could offer a cost-effective and low-toxicity approach to improving cancer treatment outcomes.