研究发现肠道细菌可以提高他莫西芬在治疗乳腺癌的有效性. Study finds gut bacteria can enhance tamoxifen's effectiveness in treating breast cancer.

在mBio进行的一项新研究表明,直肠细菌可以影响人体中常见的乳腺癌药物 -- -- 一种常见的乳癌药物 -- -- 亚甲霉素是如何起作用的。 A new study in mBio reveals that gut bacteria can affect how well tamoxifen, a common breast cancer drug, works in the body. 研究人员发现某些肠道细菌产生酶, 帮助回收他莫西芬, 这可能使其更有效. Researchers found that certain gut bacteria produce enzymes that help recycle tamoxifen, potentially making it more effective. 这一发现可能导致基于患者直肠微生物的个性化治疗,从而提高药物在预防乳腺癌复发方面的功效。 This discovery could lead to personalized treatments based on a patient's gut microbiome, improving the drug's effectiveness in preventing breast cancer recurrence.