加州大学洛杉矶分校研究人员发现,F-actin妨碍清除细胞废物,导致大脑老化和认知下降。 UCLA researchers discovered that F-actin hampers cellular waste removal, contributing to brain aging and cognitive decline.

加州大学洛杉矶分校研究人员发现,蛋白丝状蛋白作用(F-actin)抑制清除细胞废物,导致认知下降,从而助长了大脑衰老。 UCLA researchers found that the protein filamentous actin (F-actin) contributes to brain aging by inhibiting the removal of cellular waste, leading to cognitive decline. 他们通过改变老果蝇中的基因,防止了F-actin积聚,加强了细胞循环利用,并使寿命增加了约30%。 By modifying genes in aging fruit flies, they prevented F-actin buildup, enhanced cellular recycling, and increased lifespan by about 30%. 这表明,以F-actin为目标可以改善老龄化和认知健康,有可能为今后治疗人类与年龄有关的疾病提供信息。 This suggests that targeting F-actin could improve aging and cognitive health, potentially informing future treatments for age-related diseases in humans.