科比大学的研究人员在SARS-CoV-2中发现了一种酶,可以去除ISG15,从而逃避免疫防御并增加感染力. Kobe University researchers discover an enzyme in SARS-CoV-2 that removes ISG15, evading immune defenses and increasing infectivity.

神户大学的研究人员在SARS-COV-2中发现了一种酶,使病毒能够避开人体的内在免疫防护,这可能说明它比以前诸如SARS和MERS等冠状病毒的感染性更高。 Researchers at Kobe University have identified an enzyme in SARS-CoV-2 that allows the virus to evade the body's innate immune defenses, which may explain its higher infectivity compared to previous coronaviruses like SARS and MERS. 这种酶从病毒的核核细胞卡psid中除去分子标记ISG15, 方便病毒组装。 This enzyme removes a molecular tag, ISG15, from the virus's nucleocapsid, facilitating virus assembly. 调查结果可以指导针对这一机制制定更有效的抗病毒药物。 The findings could inform the development of more effective antiviral drugs targeting this mechanism.