5-FU化疗药物通过RNA合成干扰,而不是DNA损伤,杀死胃肠癌细胞。 5-FU chemotherapy drug kills gastrointestinal cancer cells via RNA synthesis interference, not DNA damage.

麻省理工学院的一项研究表明,化疗药物5-氟聚氨酯(5-FU)通过干扰RNA合成,而不是像以前想象的那样破坏DNA,在胃肠癌中杀死细胞。 A study from MIT reveals that the chemotherapy drug 5-fluorouracil (5-FU) kills cells in gastrointestinal cancers by interfering with RNA synthesis, not by damaging DNA as previously thought. 这一调查结果表明,将5U型药物与RNA定向药物相结合,可能比目前的DNA破坏组合更为有效。 This finding suggests that combining 5-FU with RNA-targeting drugs could be more effective than current DNA-damaging combinations. 这项研究可能会导致新的临床试验,目的是提高5-FU在治疗结肠癌和其他GI癌症方面的效力。 The research may lead to new clinical trials aimed at enhancing 5-FU's effectiveness in treating colon and other GI cancers.