研究人员查明了促进淋巴性转移的CAF子集,并揭示了抑制这种转移的潜在战略。 Researchers identify CAF subsets promoting lymphatic metastasis and reveal potential strategies to inhibit it.
Sun Yat-sen纪念医院的研究人员发表了一项关于癌症生物学和医学的研究,揭示了CAF在促进淋巴病转移方面的作用,淋巴病是癌症发展的一个关键因素。 Researchers from Sun Yat-sen Memorial Hospital published a study in Cancer Biology & Medicine, revealing CAFs' role in promoting lymphatic metastasis, a crucial factor in cancer progression. 该研究分析了CAF子集,这些子集通过与其他树皮细胞的相互作用,细胞因子分泌和外体细胞的产生,导致淋巴侵袭和转移. The study analyzed CAF subsets contributing to lymphatic invasion and metastasis through interactions with other stromal cells, cytokine secretion, and exosome production. 研究人员针对特定子子类子类CAF,展示了抑制淋巴病转移和改善癌症治疗的潜在战略。 By targeting specific CAF subsets, researchers demonstrated potential strategies to inhibit lymphatic metastasis and improve cancer treatments. 这项研究强调了CAF异质性在癌症进展中的重要性,并为设计向癌症治疗提供了新的途径. The study emphasizes the importance of CAF heterogeneity in cancer progression and offers new avenues for designing targeted cancer therapies.