科学家发现CRTC 与心脏肥大有关, 暗示潜在的治疗目标。 Scientists find CRTC linked to heart hypertrophy, suggesting potential therapeutic target.

Sanford Burnham Prebys和Salk研究所的科学家发现,在心脏结构和功能方面,由CREB管制的蛋白质转录共活体(CRTC)发挥了新的作用。 Scientists at Sanford Burnham Prebys and Salk Institute discovered a new role for protein CREB-regulated transcription co-activator (CRTC) in heart structure and function. 过度活跃的 CRTC 导致心脏肥大, 心脏肌肉变厚 与心脏病有关。 Overactive CRTC causes cardiac hypertrophy, a thickening of the heart muscle linked to heart disease. 这项研究使用转基因果蝇,表明CRTC可能成为较肥和其他心脏疾病的潜在治疗目标。 The research, using genetically engineered fruit flies, suggests that CRTC may be a potential therapeutic target for hypertrophy and other heart conditions.