2016 年全球生殖器疱疹感染导致 353 亿美元的医疗保健费用和生产力损失，其中 HSV-2 占 312 亿美元。 2016 global genital herpes infections resulted in $35.3bn in healthcare costs and lost productivity, with HSV-2 accounting for $31.2bn.

根据最新估计，2016 年全球生殖器疱疹感染导致 353 亿美元的医疗保健费用和生产力损失。 Global genital herpes infections led to $35.3bn in healthcare costs and lost productivity in 2016, according to new estimates. 犹他州健康大学、世界卫生组织 (WHO) 和其他学术机构的研究人员分析了 194 个国家，估计 HSV-1 的成本为 40 亿美元，HSV-2 的成本为 312 亿美元。 Researchers from the University of Utah Health, the World Health Organization (WHO), and other academic institutions analyzed 194 countries, estimating HSV-1 at $4bn and HSV-2 at $31.2bn in costs.