根据 PLOS Biology 的研究,5% 的经过动物测试的疗法获得了人类监管部门的批准。 5% of animal-tested therapies reach human regulatory approval, per PLOS Biology study.
《PLOS Biology》发表的一项研究表明,在动物身上测试的疗法中只有 5% 能够获得监管部门批准用于人类。 A study published in PLOS Biology reveals that only 5% of therapies tested on animals reach regulatory approval for human use. 对转化生物医学研究评论的分析表明,尽管转化为人体研究的比例达到 50%,但最终批准前的退出率仍然很高。 The analysis of translational biomedical research reviews shows a high drop-off rate before final approval, despite a 50% translation rate to human studies. 研究人员认为,提高实验方法的稳健性和普遍性可以增加成功翻译和最终批准的机会。 Researchers argue that improved robustness and generalizability of experimental approaches could increase the chances of successful translation and final approval.