罗格斯健康中心的研究人员发现了自闭症类型中共有的大脑发育机制,可以用现有药物纠正 mTOR 通路缺陷。 Rutgers Health researchers discovered shared brain development mechanisms in autism types, correcting mTOR pathway defects with existing medications.
一项针对不同自闭症类型的研究发现了大脑发育的共同机制,可能对现有药物产生反应。 A study of different autism types found shared mechanisms in brain development, potentially responding to existing medications. 罗格斯健康中心的研究人员将患有遗传性和不明原因自闭症的人的血细胞转化为神经前体细胞,揭示了控制结构蛋白的 mTOR 通路的缺陷。 Rutgers Health researchers transformed blood cells of people with genetic and unexplained autism into neural precursor cells, revealing defects in the mTOR pathway controlling structural proteins. 研究人员纠正了这些问题,并利用现有药物改善了细胞分化。 The researchers corrected these issues and improved cell differentiation with existing drugs.